Association between <i>ABCB1</i> rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults

Association between <i>ABCB1</i> rs2235048 Polymorphism and THC Pharmacokinetics and Subjective Effects following Smoked Cannabis in Young Adults

Genetic influences on acute responses to psychoactive drugs may contribute to individual variability in addiction risk. <i>ABCB1</i> is a human gene that encodes P-glycoprotein, an ATP-dependent efflux pump that may influence the pharmacokinetics of delta-9-tetrahydrocannabinol (THC), th...

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Bibliographic Details
Main Authors: Justin Matheson, Yollanda J. Zhang, Bruna Brands, Christine M. Wickens, Arun K. Tiwari, Clement C. Zai, James L. Kennedy, Bernard Le Foll
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Brain Sciences
Subjects:
cannabis
THC
<i>ABCB1</i>
P-glycoprotein
pharmacogenetics
Online Access:https://www.mdpi.com/2076-3425/12/9/1189

Internet

https://www.mdpi.com/2076-3425/12/9/1189

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