Syzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein and oxidative stress gene expression

Syzygium aromaticum ethanol extract reduces AlCl3-induced neurotoxicity in mice brain through regulation of amyloid precursor protein and oxidative stress gene expression

Objective: To investigate the neuroprotective effects of Syzygium aromaticum (S. aromaticum) extract (500 mg/kg) on AlCl3 (300 mg/kg)-induced mouse model of oxidative stress and neurotoxicity. Methods: An ethanolic extract of S. aromaticum seeds was prepared and the active compounds were identified...

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Bibliographic Details
Main Authors: Sanila Amber, Syed Adnan Ali Shah, Touqeer Ahmed, Saadia Zahid
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Asian Pacific Journal of Tropical Medicine
Subjects:
amyloid precursor protein
oxidative stress
aluminum
neurodegeneration
Online Access:http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=2;spage=123;epage=130;aulast=Amber

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http://www.apjtm.org/article.asp?issn=1995-7645;year=2018;volume=11;issue=2;spage=123;epage=130;aulast=Amber

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