Phenolic compounds and extracts from Crotalaria calycina Schrank potentially alleviate pain and inflammation through inhibition of cyclooxygenase-2: An in vivo and molecular dynamics studies

Phenolic compounds and extracts from Crotalaria calycina Schrank potentially alleviate pain and inflammation through inhibition of cyclooxygenase-2: An in vivo and molecular dynamics studies

Crotalaria calycina Schrank is a local Bangladeshi plant well-accepted by the tribal population for its medicinal properties. The primary approach of our study was to uncover the analgesic and anti-inflammatory potential of methanol extract of C. calycina stem in mice model with in silico molecular...

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Bibliographic Details
Main Authors: Tanoy Mazumder, Tarek Hasan, Khondoker Shahin Ahmed, Hemayet Hossain, Tushar Debnath, Esrat Jahan, Naiemur Rahman, Md. Sadikur Rahman Shuvo, A F M Shahid Ud Daula
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Crotalaria calycina
Polyphenolic compounds
HPLC-DAD analysis
Analgesic and anti-inflammatory effect
Molecular dynamics
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022036568

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http://www.sciencedirect.com/science/article/pii/S2405844022036568

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