Material property alterations for phenotypes of heart failure with preserved ejection fraction: A numerical study of subject-specific porcine models

Material property alterations for phenotypes of heart failure with preserved ejection fraction: A numerical study of subject-specific porcine models

A substantial proportion of heart failure patients have a preserved left ventricular (LV) ejection fraction (HFpEF). This condition carries a high burden of morbidity and mortality and has limited therapeutic options. left ventricular pressure overload leads to an increase in myocardial collagen con...

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Bibliographic Details
Main Authors: Jonathan Weissmann, Christopher J. Charles, A. Mark Richards, Choon Hwai Yap, Gil Marom
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
heart failure with preserved ejection fraction
phenotypes
finite element analysis
computational modelling
material properties
animal modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.1032034/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.1032034/full

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