Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

<p>Abstract</p> <p>Background</p> <p>Pancreatic cancer is characterized by constitutive activation of mitogen-activated protein kinase (MAPK). Activation of MAPK is associated with the upregulation of genes implicated in the proliferation and survival of pancreatic canc...

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Bibliographic Details
Main Authors: Furukawa Toru, Tanji Etsuko, Kuboki Yuko, Hatori Takashi, Yamamoto Masakazu, Shimizu Kyoko, Shibata Noriyuki, Shiratori Keiko
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Molecular Cancer
Subjects:
SON
MAPK
RNA interference
Speckle
Cell cycle
Online Access:http://www.molecular-cancer.com/content/11/1/88

Internet

http://www.molecular-cancer.com/content/11/1/88

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