Next-generation-sequencing-spectratyping reveals public T-cell receptor repertoires in pediatric very severe aplastic anemia and identifies a β chain CDR3 sequence associated with hepatitis-induced pathogenesis

Next-generation-sequencing-spectratyping reveals public T-cell receptor repertoires in pediatric very severe aplastic anemia and identifies a β chain CDR3 sequence associated with hepatitis-induced pathogenesis

Current diagnostic approaches that characterize T-cell deficiency by analyzing diversity of T-cell receptor sequences effectuate limited informational gain about the actual restrictiveness. For deeper insight into T-cell receptor repertoires we developed next-generation-sequencing-spectratyping, whi...

Full description

Bibliographic Details
Main Authors: Pina F. I. Krell, Susanne Reuther, Ute Fischer, Thomas Keller, Stephan Weber, Michael Gombert, Friedhelm R. Schuster, Corinna Asang, Polina Stepensky, Brigitte Strahm, Roland Meisel, Jens Stoye, Arndt Borkhardt
Format: Article
Language:English
Published: Ferrata Storti Foundation 2013-09-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/6775

Internet

https://haematologica.org/article/view/6775

Similar Items