Ex-Vivo Skin Explant Culture Is a Model for TSLP-Mediated Skin Barrier Immunity

The skin is the outermost barrier protecting the body from pathogenic invasion and environmental insults. Its breakdown initiates the start of skin inflammation. The epidermal growth factor (EGFR) on keratinocytes protects this barrier, and its dysfunction leads to atopic dermatitis-like skin diseas...

Full description

Bibliographic Details
Main Authors: Thomas Bauer, Daniela Gubi, Jörg Klufa, Philipp Novoszel, Martin Holcmann, Maria Sibilia
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/11/1237