AlphaFold-Multimer predicts cross-kingdom interactions at the plant-pathogen interface

Abstract Adapted plant pathogens from various microbial kingdoms produce hundreds of unrelated small secreted proteins (SSPs) with elusive roles. Here, we used AlphaFold-Multimer (AFM) to screen 1879 SSPs of seven tomato pathogens for interacting with six defence-related hydrolases of tomato. This s...

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Bibliographic Details
Main Authors: Felix Homma, Jie Huang, Renier A. L. van der Hoorn
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-41721-9