Successful expansion and cryopreservation of human natural killer cell line NK-92 for clinical manufacturing.

Successful expansion and cryopreservation of human natural killer cell line NK-92 for clinical manufacturing.

Natural killer (NK) cells have recently shown renewed promise as therapeutic cells for use in treating hematologic cancer indications. Despite this promise, NK cell manufacturing workflows remain largely manual, open, and disconnected, and depend on feeders, as well as outdated unit operations or pr...

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Bibliographic Details
Main Authors: Seul Lee, Yunjoo Joo, Eun Ji Lee, Youngseon Byeon, Jae-Hwan Kim, Kyoung-Ho Pyo, Young Seob Kim, Sun Min Lim, Peter Kilbride, Rohin K Iyer, Mingming Li, Mandy C French, Jung-Yub Lee, Jeeheon Kang, Hyesin Byun, Byoung Chul Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294857&type=printable

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https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0294857&type=printable

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