TIR-1/SARM1 inhibits axon regeneration and promotes axon degeneration

Growth and destruction are central components of the neuronal injury response. Injured axons that are capable of repair, including axons in the mammalian peripheral nervous system and in many invertebrate animals, often regenerate and degenerate on either side of the injury. Here we show that TIR-1/...

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Bibliographic Details
Main Authors: Victoria L Czech, Lauren C O'Connor, Brendan Philippon, Emily Norman, Alexandra B Byrne
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/80856