Access to New Cytotoxic Triterpene and Steroidal Acid-TEMPO Conjugates by Ugi Multicomponent-Reactions

Access to New Cytotoxic Triterpene and Steroidal Acid-TEMPO Conjugates by Ugi Multicomponent-Reactions

Multicomponent reactions, especially the Ugi-four component reaction (U-4CR), provide powerful protocols to efficiently access compounds having potent biological and pharmacological effects. Thus, a diverse library of betulinic acid (BA), fusidic acid (FA), cholic acid (CA) conjugates with TEMPO (ni...

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Bibliographic Details
Main Authors: Haider N. Sultani, Ibrahim Morgan, Hidayat Hussain, Andreas H. Roos, Haleh H. Haeri, Goran N. Kaluđerović, Dariush Hinderberger, Bernhard Westermann
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
multi-component reaction
fusidic acid
TEMPO-conjugate
electron paramagnetic resonance (EPR) spectroscopy
caspase-3
Online Access:https://www.mdpi.com/1422-0067/22/13/7125

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https://www.mdpi.com/1422-0067/22/13/7125

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