Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

Choice of adjuvant and antigen composition alters the immunogenic profile of a SARS-CoV-2 subunit vaccine

Introduction: Since their introduction, adjuvanted recombinant subunit vaccines against COVID-19 have played a pivotal role in protecting global populations. Optimizing the immune response’s quality, amplitude, and durability to these vaccines depends on the appropriate adjuvant choice and dose in c...

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Những tác giả chính: William R. Lykins, Jeroen Pollet, Jessica A. White, Brian Keegan, Leroy Versteeg, Ulrich Strych, Wen-Hsiang Chen, Raodoh Mohamath, Gabi Ramer-Denisoff, Sierra Reed, Samuel Beaver, Alana Gerhardt, Emily A. Voigt, Mark A. Tomai, Robert Sitrin, Robert K. M. Choy, Frederick J. Cassels, Peter J. Hotez, Maria Elena Bottazzi, Christopher B. Fox
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: Frontiers Media S.A. 2024-02-01
Loạt:Frontiers in Drug Delivery
Những chủ đề:
receptor binding domain
adjuvant formulation
SARS-CoV-2
vaccine development
toll-like receptor
bivalent vaccine
Truy cập trực tuyến:https://www.frontiersin.org/articles/10.3389/fddev.2024.1342518/full

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https://www.frontiersin.org/articles/10.3389/fddev.2024.1342518/full

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