Identification of the critical sites of NNRTI-resistance in reverse transcriptase of HIV-1 CRF_BC strains.

Identification of the critical sites of NNRTI-resistance in reverse transcriptase of HIV-1 CRF_BC strains.

BACKGROUND: The polymorphisms involved in drug resistance to non-nucleoside reverse transcriptase inhibitors (NNRTIs) in HIV-1 CRF_BC, the most prevalent HIV-1 strain in China, have been poorly characterized. RESULTS: To reveal the drug resistance mutations, we compared the gene sequences of pol reg...

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Bibliographic Details
Main Authors: Yang Huang, Zhenpeng Li, Hui Xing, Yang Jiao, Yabo Ouyang, Lingjie Liao, Shibo Jiang, Rebecca Armstrong, Yiming Shao, Liying Ma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990534?pdf=render

Internet

http://europepmc.org/articles/PMC3990534?pdf=render

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