Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model

Effect of β-hydroxybutyrate on behavioral alterations, molecular and morphological changes in CNS of multiple sclerosis mouse model

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of central nervous system (CNS). Aging is the most significant risk factor for the progression of MS. Dietary modulation (such as ketogenic diet) and caloric restriction, can increase ketone bodies, especially β-hydroxybutyra...

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Bibliographic Details
Main Authors: Wei Sun, Min Wen, Min Liu, Qingpeng Wang, Quiqin Liu, Lanjie Li, Hans-Christian Siebert, Gabriele Loers, Ruiyan Zhang, Ning Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Aging Neuroscience
Subjects:
multiple sclerosis
β-hydroxybutyrate
demyelination
TRPA1
PARP
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2022.1075161/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2022.1075161/full

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