Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations

Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations

Bone morphogenetic proteins (BMPs) are growth factors that have a vital role in the production of bone, cartilage, ligaments, and tendons. Tumors’ upregulation of bone morphogenetic proteins (BMPs) and their receptors are key features of cancer progression. Regulation of the BMP kinase system is a n...

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书目详细资料
Main Authors: Amany Belal, Hazem Elkady, Ahmed A. Al-Karmalawy, Ali H. Amin, Mohammed M. Ghoneim, Mohamed El-Sherbiny, Rasha Hamed Al-Serwi, Mohamed Attia Abdou, Mona H. Ibrahim, Ahmed B. M. Mehany
格式: 文件
语言:English
出版: MDPI AG 2022-08-01
丛编:Molecules
主题:
benzothiophene
benzofuran
BMP-2 inducible kinase
ADMET
docking
在线阅读:https://www.mdpi.com/1420-3049/27/17/5571

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https://www.mdpi.com/1420-3049/27/17/5571

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