VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function

VLDLR disturbs quiescence of breast cancer stem cells in a ligand-independent function

Breast cancer stem cells are responsible for cancer initiation, progression, and drug resistance. However, effective targeting strategies against the cell subpopulation are still limited. Here, we unveil two splice variants of very-low-density lipoprotein receptor, VLDLR-I and -II, which are highly...

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Bibliographic Details
Main Authors: Mengying Yang, Yajing Zhan, Zhijie Hou, Chunli Wang, Wenjun Fan, Tao Guo, Zhuoshi Li, Lei Fang, Shasha Lv, Sisi Li, Chundong Gu, Mingliang Ye, Hongqiang Qin, Quentin Liu, Xiaonan Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Oncology
Subjects:
VLDLR
breast cancer
cancer stem cell
quiescence
ligand-independent function
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.887035/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.887035/full

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