Dopamine-induced changes to thalamic GABA concentration in impulsive Parkinson disease patients

Abstract Impulsivity is inherent to behavioral disorders such as substance abuse and binge eating. While the role of dopamine in impulse behavior is well established, γ-aminobutyric acid (GABA) therapies have promise for the treatment of maladaptive behaviors. In Parkinson disease (PD), dopaminergic...

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Bibliographic Details
Main Authors: Paula Trujillo, Alexander K. Song, Kaitlyn R. Hay, Megan Aumann, Yan Yan, Hakmook Kang, Manus J. Donahue, Daniel O. Claassen
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-022-00298-8