Simultaneous Quantitation of Isoprenoid Pyrophosphates in Plasma and Cancer Cells Using LC-MS/MS

Isoprenoids (IsoP) are an important class of molecules involved in many different cellular processes including cholesterol synthesis. We have developed a sensitive and specific LC-MS/MS method for the quantitation of three key IsoPs in bio-matrices, geranyl pyrophosphate (GPP), farnesyl pyrophosphat...

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Autori principali: Yashpal S. Chhonker, Staci L. Haney, Veenu Bala, Sarah A. Holstein, Daryl J. Murry
Natura: Articolo
Lingua:English
Pubblicazione: MDPI AG 2018-12-01
Serie:Molecules
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Accesso online:https://www.mdpi.com/1420-3049/23/12/3275