Adenosine receptors differentially mediate enteric glial cell death induced by Clostridioides difficile Toxins A and B

Adenosine receptors differentially mediate enteric glial cell death induced by Clostridioides difficile Toxins A and B

Increased risk of intestinal dysfunction has been reported in patients after Clostridioides difficile infection (CDI). Enteric glial cells (EGCs), a component of the enteric nervous system (ENS), contribute to gut homeostasis. Previous studies showed that adenosine receptors, A2A and A2B, modulate i...

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Bibliographic Details
Main Authors: Deiziane V. S. Costa, Jae H. Shin, Sophia M. Goldbeck, David T. Bolick, Flavio S. Mesquita, Andrea V. Loureiro, Mônica J. Rodrigues-Jesus, Gerly A. C. Brito, Cirle A. Warren
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Clostridioides difficile
Clostridioides difficile infection
adenosine receptors
enteric glia
cell death
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.956326/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.956326/full

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