Clinical and molecular spectrum of P/Q type calcium channel Cav2.1 in epileptic patients

Clinical and molecular spectrum of P/Q type calcium channel Cav2.1 in epileptic patients

Abstract Background Epilepsy is a neurological disorder characterized by the potential to induce seizure and accompanied by cognitive, psychological, and social consequences. CACNA1A gene is a voltage-gated P/Q-type Cav2.1 channel that is broadly expressed in the central nervous system, and the path...

Full description

Bibliographic Details
Main Authors: Elham Alehabib, Zahra Esmaeilizadeh, Sakineh Ranji-Burachaloo, Abbas Tafakhori, Hossein Darvish, Abolfazl Movafagh
Format: Article
Language:English
Published: BMC 2021-11-01
Series:Orphanet Journal of Rare Diseases
Subjects:
CACNA1A
Epilepsy
Calcium channels
Intellectual disability
Neurodevelopmental disorder
Brain imaging abnormalities
Online Access:https://doi.org/10.1186/s13023-021-02101-y

Internet

https://doi.org/10.1186/s13023-021-02101-y

Similar Items