Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV

Female Genital Fibroblasts Diminish the In Vitro Efficacy of PrEP against HIV

The efficacy of HIV pre-exposure prophylaxis (PrEP) is high in men who have sex with men, but much more variable in women, in a manner largely attributed to low adherence. This reduced efficacy, however, could also reflect biological factors. Transmission to women is typically via the female reprodu...

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Bibliographic Details
Main Authors: Ashley F. George, Matthew McGregor, David Gingrich, Jason Neidleman, Rebecca S. Marquez, Kyrlia C. Young, Kaavya L. Thanigaivelan, Warner C. Greene, Phyllis C. Tien, Amelia N. Deitchman, Trimble L. Spitzer, Nadia R. Roan
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
HIV transmission
female reproductive tract
pre-exposure prophylaxis
fibroblasts
Online Access:https://www.mdpi.com/1999-4915/14/8/1723

Internet

https://www.mdpi.com/1999-4915/14/8/1723

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