Lower Circulating Cell-Free Mitochondrial DNA Is Associated with Heart Failure in Type 2 Diabetes Mellitus Patients

Lower Circulating Cell-Free Mitochondrial DNA Is Associated with Heart Failure in Type 2 Diabetes Mellitus Patients

Cell-free nuclear (cf-nDNA) and mitochondrial (cf-mDNA) DNA are released from damaged cells in type 2 diabetes mellitus (T2DM) patients, contributing to adverse cardiac remodeling, vascular dysfunction, and inflammation. The purpose of this study was to correlate the presence and type of cf-DNAs wit...

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Bibliographic Details
Main Authors: Tetiana A. Berezina, Mykola P. Kopytsya, Olga V. Petyunina, Alexander A. Berezin, Zeljko Obradovic, Lukas Schmidbauer, Michael Lichtenauer, Alexander E. Berezin
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cardiogenetics
Subjects:
type 2 diabetes mellitus
heart failure
cell-free DNA
liquid biopsy
biomarkers
Online Access:https://www.mdpi.com/2035-8148/13/1/3

Internet

https://www.mdpi.com/2035-8148/13/1/3

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