The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis

The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis

Tafenoquine is a newly licensed antimalarial drug for the radical cure of Plasmodium vivax malaria. The mechanism of action and optimal dosing are uncertain. We pooled individual data from 1102 patients and 72 healthy volunteers studied in the pre-registration trials. We show that tafenoquine dose i...

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Bibliographic Details
Main Authors: James A Watson, Robert J Commons, Joel Tarning, Julie A Simpson, Alejandro Llanos Cuentas, Marcus VG Lacerda, Justin A Green, Gavin CKW Koh, Cindy S Chu, François H Nosten, Richard N Price, Nicholas PJ Day, Nicholas J White
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-12-01
Series:eLife
Subjects:
tafenoquine
radical cure
Plasmodium vivax
haemolysis
Online Access:https://elifesciences.org/articles/83433

Internet

https://elifesciences.org/articles/83433

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