Read-through transcription of tRNA underlies the cell cycle-dependent dissociation of IHF from the DnaA-inactivating sequence datA

Read-through transcription of tRNA underlies the cell cycle-dependent dissociation of IHF from the DnaA-inactivating sequence datA

Timely initiation of chromosomal DNA replication in Escherichia coli is achieved by cell cycle-coordinated regulation of the replication origin, oriC, and the replication initiator, ATP-DnaA. Cellular levels of ATP-DnaA increase and peak at the time for initiation at oriC, after which hydrolysis of...

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Bibliographic Details
Main Authors: Kazutoshi Kasho, Ryuji Sakai, Kosuke Ito, Wataru Nakagaki, Rion Satomura, Takafumi Jinnouchi, Shogo Ozaki, Tsutomu Katayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Microbiology
Subjects:
E. coli
DnaA
datA
IHF
tRNA transcription
cell cycle
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1360108/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2024.1360108/full

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