Characterization of genomic instability-related genes predicts survival and therapeutic response in lung adenocarcinoma

Characterization of genomic instability-related genes predicts survival and therapeutic response in lung adenocarcinoma

Abstract Background Lung adenocarcinoma (LUAD) is the most common subtype of non-small cell lung cancer (NSCLC) and is the leading cause of cancer death worldwide. Its progression is characterized by genomic instability. In turn, the level of genomic instability affects the prognosis and immune stat...

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Bibliographic Details
Main Authors: Shuyang Li, Wei Wang, Huihan Yu, Siyu Zhang, Wenxu Bi, Suling Sun, Bo Hong, Zhiyou Fang, Xueran Chen
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Lung adenocarcinoma
Tumor immune microenvironment
Genetic signature associated with genomic instability
Chemotherapy
Immune characteristic
Online Access:https://doi.org/10.1186/s12885-023-11580-0

Internet

https://doi.org/10.1186/s12885-023-11580-0

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