Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse.

Enhanced mitochondrial superoxide scavenging does not improve muscle insulin action in the high fat-fed mouse.

Improving mitochondrial oxidant scavenging may be a viable strategy for the treatment of insulin resistance and diabetes. Mice overexpressing the mitochondrial matrix isoform of superoxide dismutase (sod2(tg) mice) and/or transgenically expressing catalase within the mitochondrial matrix (mcat(tg) m...

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Bibliographic Details
Main Authors: Daniel S Lark, Li Kang, Mary E Lustig, Jeffrey S Bonner, Freyja D James, P Darrell Neufer, David H Wasserman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4437982?pdf=render

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http://europepmc.org/articles/PMC4437982?pdf=render

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