Mild-intensity physical activity prevents cardiac and osseous iron deposition without affecting bone mechanical property or porosity in thalassemic mice

Mild-intensity physical activity prevents cardiac and osseous iron deposition without affecting bone mechanical property or porosity in thalassemic mice

Abstract Thalassemia causes anemia, ineffective erythropoiesis, bone loss and iron accumulation in several tissues, e.g., liver, bone and heart, the last of which leads to lethal cardiomyopathy and arrhythmia. Although exercise reportedly improves bone density in thalassemic mice, exercise performan...

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Main Authors: Narattaphol Charoenphandhu, Supagarn Sooksawanwit, Ratchaneevan Aeimlapa, Natchayaporn Thonapan, Pornpailin Upanan, Punyanuch Adulyaritthikul, Saowalak Krungchanuchat, Nattapon Panupinthu, Jarinthorn Teerapornpuntakit, Catleya Rojviriya, Kornkamon Lertsuwan, Saovaros Svasti, Kannikar Wongdee
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09997-x

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https://doi.org/10.1038/s41598-022-09997-x

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