Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145

Enhancement of docetaxel-induced cytotoxicity and apoptosis by all-trans retinoic acid (ATRA) through downregulation of survivin (BIRC5), MCL-1 and LTbeta-R in hormone- and drug resistant prostate cancer cell line, DU-145

<p>Abstract</p> <p>Background</p> <p>The management of hormone-refractory prostate cancer (HRPC) still remains as an important challenge of daily oncology practice. Docetaxel has proved to be a first line treatment choice. All-trans retinoic acid (ATRA) could potently i...

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Bibliographic Details
Main Authors: Karabulut Bulent, Uzunoglu Selim, Atmaca Harika, Gorumlu Gurbuz, Karaca Burcak, Erten Cigdem, Cengiz Ercument, Gul Mustafa K, Kucukzeybek Yuksel, Sanli Ulus A, Uslu Ruchan
Format: Article
Language:English
Published: BMC 2008-09-01
Series:Journal of Experimental & Clinical Cancer Research
Online Access:http://www.jeccr.com/content/27/1/37

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http://www.jeccr.com/content/27/1/37

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