Characterization of the xiamenmycin biosynthesis gene cluster in Streptomyces xiamenensis 318.

Xiamenmycin (1) is a prenylated benzopyran derivative with anti-fibrotic activity. To investigate the genetic basis of xiamenmycin biosynthesis, we performed genome mining in the xiamenmycin-producing Streptomyces xiamenensis wild-type strain 318 to identify a candidate gene cluster. The complete ge...

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Bibliographic Details
Main Authors: Yong Yang, Ling Fu, Jinlong Zhang, Linghan Hu, Minjuan Xu, Jun Xu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24919072/?tool=EBI