Systemic depletion of lymphocytes following focal radiation to the brain in a murine model

Severe radiation-related lymphopenia is common and associated with decreased survival in patients with several solid tumors. As the mechanisms underlying systemic lymphopenia are poorly understood, we developed an animal model to study the effects of brain radiation on lymphocytes and cytokines. C57...

Full description

Bibliographic Details
Main Authors: Anna F. Piotrowski, Thomas R. Nirschl, Esteban Velarde, Lee Blosser, Sudipto Ganguly, Kathleen H. Burns, Leo Luznik, John Wong, Charles G. Drake, Stuart A. Grossman
Format: Article
Language:English
Published: Taylor & Francis Group 2018-07-01
Series:OncoImmunology
Subjects:
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1445951