Efficacy of Treatments Targeting Hypothalamic-Pituitary-Adrenal Systems for Major Depressive Disorder: A Meta-Analysis

Efficacy of Treatments Targeting Hypothalamic-Pituitary-Adrenal Systems for Major Depressive Disorder: A Meta-Analysis

Abnormal hypothalamic-pituitary-adrenal (HPA) axis has been implicated in major depressive disorder (MDD). A number of studies have attempted to use HPA-modulating medications to treat depression. However, their results are inconsistent. The efficacy of these drugs for MDD remains uncertain. The aim...

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Bibliographic Details
Main Authors: Yudan Ding, Zirou Wei, Haohao Yan, Wenbin Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Pharmacology
Subjects:
depression
hypothalamic-pituitary-adrenal (HPA) axis
mifepristone
vasopressin 1B receptor antagonist
randomized controlled trials (RCTs)
drug effect
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.732157/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2021.732157/full

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