Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing through miR-762 mediated promotion of keratinocytes and endothelial cells migration

Exosomes from human induced pluripotent stem cells-derived keratinocytes accelerate burn wound healing through miR-762 mediated promotion of keratinocytes and endothelial cells migration

Abstract Background The use of keratinocytes derived from induced pluripotent stem cells (iPSCs-KCs) may represent a novel cell therapy strategy for burn treatment. There is growing evidence that extracellular vesicles, including exosomes, are primary mediators of the benefits of stem cell therapy....

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Bibliographic Details
Main Authors: Yunyao Bo, Lijun Yang, Baiting Liu, Guiping Tian, Chenxi Li, Lin Zhang, Yuan Yan
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Journal of Nanobiotechnology
Subjects:
Exosome
Burn
Induced pluripotent stem cells
Keratinocytes
Endothelial cell
Online Access:https://doi.org/10.1186/s12951-022-01504-8

Internet

https://doi.org/10.1186/s12951-022-01504-8

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