Genetically Engineered Probiotic <i>Limosilactobacillus reuteri</i> Releasing IL-22 (LR-IL-22) Modifies the Tumor Microenvironment, Enabling Irradiation in Ovarian Cancer

Despite recent advances in cancer therapy, ovarian cancer remains the most lethal gynecological cancer worldwide, making it crucial and of the utmost importance to establish novel therapeutic strategies. Adjuvant radiotherapy has been assessed historically, but its use was limited by intestinal toxi...

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Bibliographic Details
Main Authors: Diala F. Hamade, Michael W. Epperly, Renee Fisher, Wen Hou, Donna Shields, Jan-Peter van Pijkeren, Brian J. Leibowitz, Lan G. Coffman, Hong Wang, M. Saiful Huq, Ziyu Huang, Claude J. Rogers, Anda M. Vlad, Joel S. Greenberger, Amitava Mukherjee
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/16/3/474