Design, synthesis, anticancer evaluation and molecular docking studies of 1,2,3-triazole incorporated 1,3,4-oxadiazole-Triazine derivatives

Design, synthesis, anticancer evaluation and molecular docking studies of 1,2,3-triazole incorporated 1,3,4-oxadiazole-Triazine derivatives

A new library of 1,2,3-triazole-incorporated 1,3,4-oxadiazole-triazine derivatives (9a-j) was designed, synthesized, and tested in vitro for anticancer activity against PC3 and DU-145 (prostate cancer), A549 (lung cancer), and MCF-7 (breast cancer) cancer cell lines using the MTT assay with etoposid...

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Bibliographic Details
Main Authors: Sujana Oggu, Parameswari Akshinthala, Naresh Kumar Katari, Laxmi Kumari Nagarapu, Srimannarayana Malempati, Rambabu Gundla, Sreekantha Babu Jonnalagadda
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Heliyon
Subjects:
Altretamine
1,3,5-Triazine
1,2,3-Triazole
Mubritinib
Anticancer activity
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023031420

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http://www.sciencedirect.com/science/article/pii/S2405844023031420

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