In vivo antiangiogenic effect of nimbolide, trans-chalcone and piperine for use against glioblastoma

In vivo antiangiogenic effect of nimbolide, trans-chalcone and piperine for use against glioblastoma

Abstract Background Angiogenesis is an important hallmark of Glioblastoma (GBM) marked by elevated vascular endothelial growth factor-A (VEGF-A) and its receptor 2 (VEGFR-2). As previously reported nimbolide (NBL), trans-chalcone (TC) and piperine (PPR) possess promising antiangiogenic activity in s...

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Bibliographic Details
Main Authors: Anna Senrung, Tanya Tripathi, Joni Yadav, Divya Janjua, Apoorva Chaudhary, Arun Chhokar, Nikita Aggarwal, Udit Joshi, Nidhi Goswami, Alok Chandra Bharti
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Glioblastoma multiforme
3D-spheroids
Chick CAM model
Angiogenesis
U87 xenograft
Online Access:https://doi.org/10.1186/s12885-023-11625-4

Internet

https://doi.org/10.1186/s12885-023-11625-4

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