Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

Cells infected with Epstein-Barr virus (EBV) express the virus-encoded EBNA1, which is essential for viral genome maintenance but also highly antigenic. Here the authors implicate nucleolin as a host factor that mediates the repression of EBNA1-derived antigenic peptides through binding of the G4-qu...

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Bibliographic Details
Main Authors: María José Lista, Rodrigo Prado Martins, Olivier Billant, Marie-Astrid Contesse, Sarah Findakly, Pierre Pochard, Chrysoula Daskalogianni, Claire Beauvineau, Corinne Guetta, Christophe Jamin, Marie-Paule Teulade-Fichou, Robin Fåhraeus, Cécile Voisset, Marc Blondel
Format: Article
Language:English
Published: Nature Portfolio 2017-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms16043

Internet

https://doi.org/10.1038/ncomms16043

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