Comparing the Characteristics of Microglia Preparations Generated Using Different Human iPSC-Based Differentiation Methods to Model Neurodegenerative Diseases

As the resident immune cells of the healthy nervous system, homeostatic microglia can rapidly become activated in response to injury/disease. Dysregulated microglia activation is a hallmark of nervous system disorders including neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) a...

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Bibliographic Details
Main Authors: Ye Man Tang, Nisha S. Pulimood, Stefano Stifani
Format: Article
Language:English
Published: Taylor & Francis 2022-12-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/17590914221145105