Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models

Enhanced Co-Expression Extrapolation (COXEN) Gene Selection Method for Building Anti-Cancer Drug Response Prediction Models

The co-expression extrapolation (COXEN) method has been successfully used in multiple studies to select genes for predicting the response of tumor cells to a specific drug treatment. Here, we enhance the COXEN method to select genes that are predictive of the efficacies of multiple drugs for buildin...

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Bibliographic Details
Main Authors: Yitan Zhu, Thomas Brettin, Yvonne A. Evrard, Fangfang Xia, Alexander Partin, Maulik Shukla, Hyunseung Yoo, James H. Doroshow, Rick L. Stevens
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Genes
Subjects:
general drug response prediction model
gene selection
co-expression extrapolation (COXEN)
precision oncology
Online Access:https://www.mdpi.com/2073-4425/11/9/1070

Internet

https://www.mdpi.com/2073-4425/11/9/1070

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