Alternative oxidase dependent respiration leads to an increased mitochondrial content in two long-lived mutants of the aging model Podospora anserina.

The retrograde response constitutes an important signalling pathway from mitochondria to the nucleus which induces several genes to allow compensation of mitochondrial impairments. In the filamentous ascomycete Podospora anserina, an example for such a response is the induction of a nuclear-encoded...

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Bibliographic Details
Main Authors: Christian Q Scheckhuber, Koen Houthoofd, Andrea C Weil, Alexandra Werner, Annemie De Vreese, Jacques R Vanfleteren, Heinz D Osiewacz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21305036/pdf/?tool=EBI