Complement-targeting therapeutics for ischemia-reperfusion injury in transplantation and the potential for ex vivo delivery

Organ shortages and an expanding waitlist have led to increased utilization of marginal organs. All donor organs are subject to varying degrees of IRI during the transplant process. Extended criteria organs, including those from older donors and organs donated after circulatory death are especially...

Full description

Bibliographic Details
Main Authors: Isabel F. Delaura, Qimeng Gao, Imran J. Anwar, Nader Abraham, Riley Kahan, Matthew G. Hartwig, Andrew S. Barbas
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1000172/full