Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism.

Dtorsin, the Drosophila ortholog of the early-onset dystonia TOR1A (DYT1), plays a novel role in dopamine metabolism.

Dystonia represents the third most common movement disorder in humans. At least 15 genetic loci (DYT1-15) have been identified and some of these genes have been cloned. TOR1A (formally DYT1), the gene responsible for the most common primary hereditary dystonia, encodes torsinA, an AAA ATPase family...

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Bibliographic Details
Main Authors: Noriko Wakabayashi-Ito, Olugbenga M Doherty, Hideaki Moriyama, Xandra O Breakefield, James F Gusella, Janis M O'Donnell, Naoto Ito
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3192163?pdf=render

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http://europepmc.org/articles/PMC3192163?pdf=render

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