The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation

The IRE1α Arm of UPR Regulates Muscle Cells Immune Characters by Restraining p38 MAPK Activation

Skeletal muscle repair and systemic inflammation/immune responses are linked to endoplasmic reticulum stress (ER stress) pathways in myopathic muscle, and muscle cells play an active role in muscular immune reactions by exhibiting immunological characteristics under persistent proinflammation stimul...

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Bibliographic Details
Main Authors: RuiCai Gu, Tao Huang, JiangWei Xiao, ZhaoHong Liao, JunHua Li, HaiQiang Lan, Jun Ouyang, JiJie Hu, Hua Liao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Physiology
Subjects:
myotubes
endoplasmic reticulum stress
unfolded protein responses
inositol-requiring enzyme 1α
p38 MAPK
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.01198/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.01198/full

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