7,8-Dihydroxyflavone induces mitochondrial apoptosis and down-regulates the expression of ganglioside GD3 in malignant melanoma cells

Abstract Malignant melanoma is a skin cancer with poor prognosis and high resistance to conventional treatment. 7,8-dihydroxyflavone (7,8-DHF) has shown anti-carcinogenic, anti-inflammatory, anti-oxidant, and pharmacological effects in several types of cancer. However, the relationship between gangl...

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Bibliographic Details
Main Authors: Won Seok Ju, Sang Young Seo, Seong-eun Mun, Kyongtae Kim, Jin Ok Yu, Jae-Sung Ryu, Ji-Su Kim, Young-Kug Choo
Format: Article
Language:English
Published: Springer 2023-03-01
Series:Discover Oncology
Subjects:
Online Access:https://doi.org/10.1007/s12672-023-00643-0