Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins.

Rhabdomyosarcoma and Wilms tumors contain a subpopulation of noggin producing, myogenic cells immunoreactive for lens beaded filament proteins.

Myo/Nog cells are identified by their expression of the skeletal muscle specific transcription factor MyoD and the bone morphogenetic protein inhibitor noggin, and binding of the G8 monoclonal antibody. Their release of noggin is critical for morphogenesis and skeletal myogenesis. In the adult, Myo/...

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Bibliographic Details
Main Authors: Jacquelyn Gerhart, Kathryn Behling, Michele Paessler, LaBraya Milton, Gregory Bramblett, Denise Garcia, Meghan Pitts, Reginald Hurtt, Mitchell Crawford, Richard Lackman, Daniela Nguyen, Joseph Infanti, Paul FitzGerald, Mindy George-Weinstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0214758

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https://doi.org/10.1371/journal.pone.0214758

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