Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies

Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies

Abstract Background Hematopoiesis within the bone marrow (BM) is a complex and tightly regulated process predominantly influenced by immune factors. Aging, diabetes, and obesity are significant contributors to BM niche damage, which can alter hematopoiesis and lead to the development of clonal hemat...

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Bibliographic Details
Main Authors: Yang Xinyi, Reshetov Igor Vladimirovich, Narasimha M. Beeraka, Allaka Satyavathi, Dinisha Kamble, Vladimir N. Nikolenko, Allaka Naga Lakshmi, Basappa Basappa, Padmanabha Reddy Y, Ruitai Fan, Junqi Liu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Stem Cell Research & Therapy
Subjects:
Hematological malignancies
Aging
Epigenetics
Clonal hematopoiesis
Obesity
Diabetes
Online Access:https://doi.org/10.1186/s13287-024-04008-4

Internet

https://doi.org/10.1186/s13287-024-04008-4

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