Disulfide bridge-targeted metabolome mining unravels an antiparkinsonian peptide

Disulfide bridge-targeted metabolome mining unravels an antiparkinsonian peptide

Peptides are a particular molecule class with inherent attributes of some small-molecule drugs and macromolecular biologics, thereby inspiring continuous searches for peptides with therapeutic and/or agrochemical potentials. However, the success rate is decreasing, presumably because many interestin...

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Bibliographic Details
Main Authors: Zhiwu Tong, Xiahong Xie, Huiming Ge, Ruihua Jiao, Tingting Wang, Xincun Wang, Wenying Zhuang, Gang Hu, Renxiang Tan
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Fungal RiPPs
Biosynthesis
Macrocyclic peptide
Acalitide
Antiparkinsonian
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523003593

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http://www.sciencedirect.com/science/article/pii/S2211383523003593

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