Plasma untargeted metabolomics with proteinase K discloses phospholipid signature associated with pulmonary arterial hypertension

Abstract Pulmonary arterial hypertension is a rare but life-threatening and clinically heterogeneous disease. The diagnostic schedule of this disorder is complex, and no specific indicator of the arterial etiology has been explored. In this study, untargeted plasma metabolomics was applied to evalua...

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Bibliographic Details
Main Authors: Renata Wawrzyniak, Margot Biesemans, Alicja Kugacka-Dąbrowska, Ewa Lewicka, Rafał Bartoszewski, Michał J. Markuszewski
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-42293-w