Iron uptake pathway of Escherichia coli as an entry route for peptide nucleic acids conjugated with a siderophore mimic

Iron uptake pathway of Escherichia coli as an entry route for peptide nucleic acids conjugated with a siderophore mimic

Bacteria secrete various iron-chelators (siderophores), which scavenge Fe3+ from the environment, bind it with high affinity, and retrieve it inside the cell. After the Fe3+ uptake, bacteria extract the soluble iron(II) from the siderophore. Ferric siderophores are transported inside the cell via th...

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Bibliographic Details
Main Authors: Uladzislava Tsylents, Michał Burmistrz, Monika Wojciechowska, Jan Stępień, Piotr Maj, Joanna Trylska
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Microbiology
Subjects:
peptide nucleic acid (PNA)
siderophores
iron coordination
TonB-dependent transport system
E. coli outer-membrane receptors
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1331021/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2024.1331021/full

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