Integration of (S)-2,3-oxidosqualene enables E. coli to become Iron Man E. coli with improved overall tolerance

Integration of (S)-2,3-oxidosqualene enables E. coli to become Iron Man E. coli with improved overall tolerance

Abstract Background While representing a model bacterium and one of the most used chassis in biomanufacturing, performance of Escherichia coli is often limited by severe stresses. A super-robust E. coli chassis that could efficiently tolerant multiple severe stresses is thus highly desirable. Sterol...

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Bibliographic Details
Main Authors: Wenjie Sun, Yun Chen, Mengkun Li, Syed Bilal Shah, Tianfu Wang, Jin Hou, Linquan Bai, Yan Feng, Zaigao Tan
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Biotechnology for Biofuels and Bioproducts
Subjects:
Sterols biosynthesis
(S)-2,3-oxidosqualene
E. coli
Severe stresses
Chemicals production
Online Access:https://doi.org/10.1186/s13068-023-02444-7

Internet

https://doi.org/10.1186/s13068-023-02444-7

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