Dysregulated Expression of CD28 and CTLA-4 Molecules in Patients with Acute Myeloid Leukemia and Possible Association with Development of Graft <em>versus</em> Host Disease after Hematopoietic Stem Cell Transplantation

Dysregulated Expression of CD28 and CTLA-4 Molecules in Patients with Acute Myeloid Leukemia and Possible Association with Development of Graft <em>versus</em> Host Disease after Hematopoietic Stem Cell Transplantation

Background: Dysregulated expression of co-stimulatory molecules is one of the immune escape mechanisms employed in hematologic malignancies like acute myeloid leukemia (AML). Objective: To evaluate the expression of the CD28 and CTLA-4 molecules in 62 adults with de novo AML and its correlation wit...

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Bibliographic Details
Main Authors: M Ramzi, M Iravani Saadi, R Yaghobi, N Arandi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2019-05-01
Series:International Journal of Organ Transplantation Medicine
Subjects:
Acute graft versus host disease (aGVHD)
AML
Co-stimulatory molecules
Hematopoietic stem cell transplantation (HSCT)
Online Access:http://www.ijotm.com/ojs/index.php/IJOTM/article/view/610

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http://www.ijotm.com/ojs/index.php/IJOTM/article/view/610

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